Brain perfusion differences in Parkinsonian disorders
Identifieur interne : 000380 ( Main/Exploration ); précédent : 000379; suivant : 000381Brain perfusion differences in Parkinsonian disorders
Auteurs : Noriyuki Kimura [Japon] ; Syojirou Hanaki [Japon] ; Teruaki Masuda [Japon] ; Takuya Hanaoka [Japon] ; Yusuke Hazama [Japon] ; Toshio Okazaki [Japon] ; Ryuki Arakawa [Japon] ; Toshihide Kumamoto [Japon]Source :
- Movement Disorders [ 0885-3185 ] ; 2011-12.
English descriptors
- KwdEn :
Abstract
We aimed to objectively examine the brain perfusion differences between PD, Parkinson variant of multiple system atrophy, and progressive supranuclear palsy. 99mTc ethylcysteinate dimer single‐photon emission CT (SPECT) was performed in 28 patients with PD, 12 with Parkinson variant of multiple system atrophy, 19 with progressive supranuclear palsy, and 17 age‐ and sex‐matched control subjects. A voxel‐by‐voxel group analysis, using statistical parametric mapping 8, was performed to detect the differences of regional cerebral blood flow among three diseases and control groups. Regional cerebral blood flow was measured using the noninvasive Patlak plot method and calculated using a fully automated region of interest technique. Progressive supranuclear palsy showed decreased regional cerebral blood flow in the cingulate gyrus and thalamus, whereas Parkinson variant of multiple system atrophy showed decreased regional cerebral blood flow in the cerebellum, compared with other patients and controls. Regional cerebral blood flow in the thalamus could be used to discriminate progressive supranuclear palsy from other diseases and control subjects with high sensitivity. These findings suggest that parkinsonian disorders, such as PD, Parkinson variant of multiple system atrophy, and progressive supranuclear palsy show a distinct SPECT pattern in the frontal cortex, thalamus, and cerebellum. Moreover, the measurements of regional cerebral blood flow in the thalamus and cerebellum may be helpful in screening for the differential diagnosis of parkinsonian syndrome. © 2011 Movement Disorder Society
Url:
DOI: 10.1002/mds.23915
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Brain perfusion differences in Parkinsonian disorders</title><author><name sortKey="Kimura, Noriyuki" sort="Kimura, Noriyuki" uniqKey="Kimura N" first="Noriyuki" last="Kimura">Noriyuki Kimura</name></author><author><name sortKey="Hanaki, Syojirou" sort="Hanaki, Syojirou" uniqKey="Hanaki S" first="Syojirou" last="Hanaki">Syojirou Hanaki</name></author><author><name sortKey="Masuda, Teruaki" sort="Masuda, Teruaki" uniqKey="Masuda T" first="Teruaki" last="Masuda">Teruaki Masuda</name></author><author><name sortKey="Hanaoka, Takuya" sort="Hanaoka, Takuya" uniqKey="Hanaoka T" first="Takuya" last="Hanaoka">Takuya Hanaoka</name></author><author><name sortKey="Hazama, Yusuke" sort="Hazama, Yusuke" uniqKey="Hazama Y" first="Yusuke" last="Hazama">Yusuke Hazama</name></author><author><name sortKey="Okazaki, Toshio" sort="Okazaki, Toshio" uniqKey="Okazaki T" first="Toshio" last="Okazaki">Toshio Okazaki</name></author><author><name sortKey="Arakawa, Ryuki" sort="Arakawa, Ryuki" uniqKey="Arakawa R" first="Ryuki" last="Arakawa">Ryuki Arakawa</name></author><author><name sortKey="Kumamoto, Toshihide" sort="Kumamoto, Toshihide" uniqKey="Kumamoto T" first="Toshihide" last="Kumamoto">Toshihide Kumamoto</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:8E23D893BE5A9AB37A2192BB335DBCDECFD63617</idno><date when="2011" year="2011">2011</date><idno type="doi">10.1002/mds.23915</idno><idno type="url">https://api.istex.fr/document/8E23D893BE5A9AB37A2192BB335DBCDECFD63617/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">000D99</idno><idno type="wicri:Area/Main/Curation">000C34</idno><idno type="wicri:Area/Main/Exploration">000380</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Brain perfusion differences in Parkinsonian disorders</title><author><name sortKey="Kimura, Noriyuki" sort="Kimura, Noriyuki" uniqKey="Kimura N" first="Noriyuki" last="Kimura">Noriyuki Kimura</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Internal Medicine III, Oita University, Faculty of Medicine, Oita</wicri:regionArea><wicri:noRegion>Oita</wicri:noRegion></affiliation></author><author><name sortKey="Hanaki, Syojirou" sort="Hanaki, Syojirou" uniqKey="Hanaki S" first="Syojirou" last="Hanaki">Syojirou Hanaki</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Internal Medicine III, Oita University, Faculty of Medicine, Oita</wicri:regionArea><wicri:noRegion>Oita</wicri:noRegion></affiliation></author><author><name sortKey="Masuda, Teruaki" sort="Masuda, Teruaki" uniqKey="Masuda T" first="Teruaki" last="Masuda">Teruaki Masuda</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Internal Medicine III, Oita University, Faculty of Medicine, Oita</wicri:regionArea><wicri:noRegion>Oita</wicri:noRegion></affiliation></author><author><name sortKey="Hanaoka, Takuya" sort="Hanaoka, Takuya" uniqKey="Hanaoka T" first="Takuya" last="Hanaoka">Takuya Hanaoka</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Internal Medicine III, Oita University, Faculty of Medicine, Oita</wicri:regionArea><wicri:noRegion>Oita</wicri:noRegion></affiliation></author><author><name sortKey="Hazama, Yusuke" sort="Hazama, Yusuke" uniqKey="Hazama Y" first="Yusuke" last="Hazama">Yusuke Hazama</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Internal Medicine III, Oita University, Faculty of Medicine, Oita</wicri:regionArea><wicri:noRegion>Oita</wicri:noRegion></affiliation></author><author><name sortKey="Okazaki, Toshio" sort="Okazaki, Toshio" uniqKey="Okazaki T" first="Toshio" last="Okazaki">Toshio Okazaki</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Internal Medicine III, Oita University, Faculty of Medicine, Oita</wicri:regionArea><wicri:noRegion>Oita</wicri:noRegion></affiliation></author><author><name sortKey="Arakawa, Ryuki" sort="Arakawa, Ryuki" uniqKey="Arakawa R" first="Ryuki" last="Arakawa">Ryuki Arakawa</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Internal Medicine III, Oita University, Faculty of Medicine, Oita</wicri:regionArea><wicri:noRegion>Oita</wicri:noRegion></affiliation></author><author><name sortKey="Kumamoto, Toshihide" sort="Kumamoto, Toshihide" uniqKey="Kumamoto T" first="Toshihide" last="Kumamoto">Toshihide Kumamoto</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Internal Medicine III, Oita University, Faculty of Medicine, Oita</wicri:regionArea><wicri:noRegion>Oita</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2011-12">2011-12</date><biblScope unit="volume">26</biblScope><biblScope unit="issue">14</biblScope><biblScope unit="page" from="2530">2530</biblScope><biblScope unit="page" to="2537">2537</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">8E23D893BE5A9AB37A2192BB335DBCDECFD63617</idno><idno type="DOI">10.1002/mds.23915</idno><idno type="ArticleID">MDS23915</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>FineSRT</term><term>Parkinson variant of multiple system atrophy</term><term>Parkinson's disease</term><term>brain perfusion SPECT</term><term>progressive supranuclear palsy</term><term>statistical parametric mapping 8</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We aimed to objectively examine the brain perfusion differences between PD, Parkinson variant of multiple system atrophy, and progressive supranuclear palsy. 99mTc ethylcysteinate dimer single‐photon emission CT (SPECT) was performed in 28 patients with PD, 12 with Parkinson variant of multiple system atrophy, 19 with progressive supranuclear palsy, and 17 age‐ and sex‐matched control subjects. A voxel‐by‐voxel group analysis, using statistical parametric mapping 8, was performed to detect the differences of regional cerebral blood flow among three diseases and control groups. Regional cerebral blood flow was measured using the noninvasive Patlak plot method and calculated using a fully automated region of interest technique. Progressive supranuclear palsy showed decreased regional cerebral blood flow in the cingulate gyrus and thalamus, whereas Parkinson variant of multiple system atrophy showed decreased regional cerebral blood flow in the cerebellum, compared with other patients and controls. Regional cerebral blood flow in the thalamus could be used to discriminate progressive supranuclear palsy from other diseases and control subjects with high sensitivity. These findings suggest that parkinsonian disorders, such as PD, Parkinson variant of multiple system atrophy, and progressive supranuclear palsy show a distinct SPECT pattern in the frontal cortex, thalamus, and cerebellum. Moreover, the measurements of regional cerebral blood flow in the thalamus and cerebellum may be helpful in screening for the differential diagnosis of parkinsonian syndrome. © 2011 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Japon</li></country></list><tree><country name="Japon"><noRegion><name sortKey="Kimura, Noriyuki" sort="Kimura, Noriyuki" uniqKey="Kimura N" first="Noriyuki" last="Kimura">Noriyuki Kimura</name></noRegion><name sortKey="Arakawa, Ryuki" sort="Arakawa, Ryuki" uniqKey="Arakawa R" first="Ryuki" last="Arakawa">Ryuki Arakawa</name><name sortKey="Hanaki, Syojirou" sort="Hanaki, Syojirou" uniqKey="Hanaki S" first="Syojirou" last="Hanaki">Syojirou Hanaki</name><name sortKey="Hanaoka, Takuya" sort="Hanaoka, Takuya" uniqKey="Hanaoka T" first="Takuya" last="Hanaoka">Takuya Hanaoka</name><name sortKey="Hazama, Yusuke" sort="Hazama, Yusuke" uniqKey="Hazama Y" first="Yusuke" last="Hazama">Yusuke Hazama</name><name sortKey="Kumamoto, Toshihide" sort="Kumamoto, Toshihide" uniqKey="Kumamoto T" first="Toshihide" last="Kumamoto">Toshihide Kumamoto</name><name sortKey="Masuda, Teruaki" sort="Masuda, Teruaki" uniqKey="Masuda T" first="Teruaki" last="Masuda">Teruaki Masuda</name><name sortKey="Okazaki, Toshio" sort="Okazaki, Toshio" uniqKey="Okazaki T" first="Toshio" last="Okazaki">Toshio Okazaki</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000380 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000380 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:8E23D893BE5A9AB37A2192BB335DBCDECFD63617
|texte= Brain perfusion differences in Parkinsonian disorders
}}
| This area was generated with Dilib version V0.6.23. |  |